Antiplasmodial Activity of Gnetum gnemon Leaves and Compounds Isolated from them
نویسندگان
چکیده
منابع مشابه
Stilbenoids isolated from the seeds of Melinjo (Gnetum gnemon L.) and their biological activity.
A 50% EtOH extract of the dried endosperms of melinjo (Gnetum gnemon L.) was purified by a combination of column chromatography, including highly porous polymer, octadecylated silica (ODS), hydroxypropylated dextran (LH-20), and silica gel, resulting in the isolation of a new stilbenoid 1, named gnetin L, along with five previously identified stilbenoids 2-6 (gnetin C, gnemonosides A, C, and D,...
متن کاملThree new trimeric stilbenes from Gnetum gnemon.
Three stilbene trimers (gnemonols D, E, F) were isolated from the root of Gnetum gnemon. The structures were determined by spectroscopic analysis. In addition, the antioxidant activity of the compounds on lipid peroxide inhibition and super oxide scavenging activity were also investigated.
متن کاملAntiplasmodial Compounds from Leaves of Dodonaea angustifolia
Background Dodonaea angustifolia is used in Ethiopian traditional medicine to treat malaria. The objective of this work was to conduct bioassay guided fractionation of the leaves of D. angustifolia using Plasmodium berghei infected mice. Method The antiplasmodial activity of the extracts and pure compounds was evaluated using the standard Peter's four-day suppressive method. The structures of...
متن کاملAntiplasmodial Activity of Isolated Polyphenols from Alectryon serratus Leaves Against 3D7 Plasmodium falciparum
Background Alectryon serratus was selected from a screening program devoted to search naturally occurring antimalarial compound from plants in Alas Purwo National Park, Banyuwangi, East Java, Indonesia. The previous studies showed that ethanol extract of A. serratus leaves contains some polyphenol compounds. Objective This study was designed to isolate and investigate antiplasmodial activity ...
متن کاملInhibitory effect of gnetin C, a resveratrol dimer from melinjo (Gnetum gnemon), on tyrosinase activity and melanin biosynthesis.
Tyrosinase is the key enzyme involved in melanogenesis. The aim of this study was to investigate the in vitro inhibitory effects of gnetin C, a resveratrol dimer isolated from melinjo (Gnetum gnemon) seeds, on tyrosinase activity and melanin biosynthesis in murine B16 cells. The inhibitory activities of gnetin C and resveratrol were shown to be almost equal against tyrosinase and melanin biosyn...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2018
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1801301007